Busulfan Injection Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Busulfan Injection is safe in breast-feeding or not.

What is Busulfan Injection used for?

Busulfan injection is indicated for use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia. Busulfan injection is an alkylating drug indicated for: Use in combination with cyclophosphamide as a conditioning regimen prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia (CML). (1)

Is Busulfan Injection usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Busulfan Injection dangerous while breastfeeding
Our analysis of Busulfan which are active ingredients in Busulfan Injection indicates that Busulfan Injection is dangerous to use in breastfeeding. We strongly recommend you to go through detailed analysis of Busulfan as below and do not use Busulfan Injection during breastfeeding.

Busulfan Injection Breastfeeding Analsys

Busulfan while Breastfeeding


CAS Number: 55-98-1

Drug is cleared from the body in 10 elimination half-lives. Resuming breastfeeding is likely safe after 24 hours of pumping-and-dumping.

Busulfan Injection Breastfeeding Analsys - 2

Busulfan while Breastfeeding

CAS Number: 55-98-1

Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy.[1] It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence. Although minimal data are available to determine an appropriate period to withhold breastfeeding, the drug's terminal half-live of 2.5 hours suggests that withholding breastfeeding for at least 24 hours may be sufficient. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[2] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[3]

I am nursing mother and I have already used Busulfan Injection, what should I do?

You should immediately inform your health care provider about Busulfan Injection usage and your breastfeeding interval after usage of . If you feel baby is having abnormal behavior or any other health issue please call 911 immediately or contact nearest medical emergency center.

I am nursing mother and my doctor has suggested me to use Busulfan Injection, is it safe?

Please double check with your doctor if he is aware of your breastfeeding stratus, Ask your doctor if there is any safe alternative of Busulfan Injection. Check with your doctor if you shall temporally stop breastfeeding. You may go for second opinion as well. Still after all of this if your doctor still recommends Busulfan Injection then go for it as they have access on more detailed medical and scientific information and they understand your individual medical situation much better.

If I am using Busulfan Injection, will my baby need extra monitoring?

Extreme level of monitoring required as Busulfan Injection could be dangerous for kid.

Who can I talk to if I have questions about usage of Busulfan Injection in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week