CAS Number: 58-73-1
It is a first generation antihistamine drug (Ethanolamine) with a strong sedative effect. A high protein-binding capacity makes difficult an excretion into breast milk in significant amounts in accordance with old studies that had confirmed it. The absorption from ingested mother's milk to the infant's plasma is hampered by a low oral bioavailability. For both, the mother and the infant is safer the use of antihistamine medication with higher safety levels without sedative effect, especially when the child is a premature or younger than 1 month old. Neither a decrease of milk production nor alteration of Prolactin release have been shown with the use of this drug. When used while breastfeeding do it with the lower dose as possible and avoid a long-term use. Check up for feeding difficulty and somnolence in the infant. Bed-sharing with the infant is not recommended for parents who are on this medication.
CAS Number: 58-73-1
Small, occasional doses of diphenhydramine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug. The nonsedating antihistamines are preferred alternatives.
Pharbedryl | Diphenhydramine Hcl 50mg Capsule is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Pharbedryl | Diphenhydramine Hcl 50mg Capsule so you should inform him based on your convenience.
Though Pharbedryl | Diphenhydramine Hcl 50mg Capsule dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.
Not much monitoring required while using Pharbedryl | Diphenhydramine Hcl 50mg Capsule
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