Apriso | Mesalamine 375 Mg Breastfeeding
It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Apriso | Mesalamine 375 Mg is safe for baby while breastfed.

What is Apriso | Mesalamine 375 Mg used for?

APRISO capsules are indicated for the maintenance of remission of ulcerative colitis in patients 18 years of age and older. •APRISO is a locally-acting aminosalicylate indicated for the maintenance of remission of ulcerative colitis in adults. (1)

I am breastfeeding mother and I am using Apriso | Mesalamine 375 Mg. Can it have any bad effect on my kid? Shall I search for better alternative?

Apriso | Mesalamine 375 Mg safe for breastfeeding
Mesalamine is the only one ingredient used in manufacturing of Apriso | Mesalamine 375 Mg, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Mesalamine it is safe to use Apriso | Mesalamine 375 Mg while lactating. We suggest you to check further details below about Mesalamine usage in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Low concentrations of mesalamine and higher concentrations of its N-acetyl metabolite have been detected in human breast milk. The clinical significance of this has not been determined and there is limited experience of nursing women using mesalamine. Caution should be exercised when APRISO is administered to a nursing woman.

Apriso | Mesalamine 375 Mg Breastfeeding Analsys

Mesalamine while Breastfeeding


CAS Number: 89-57-6

Mesalazine is badly absorbed by the intestine, serum levels are low with scant excretion into breast milk. N-acetyl-5-ASA is an inactive metabolite which is excreted into breast milk but not higher than 10% of relative infant's dose. No harm effects among breastfed infants from treated mothers have been reported, except for rare cases of diarrhea reported in the 80's with the use of Mesalazine compounds different to Balsalazide. In a review of 121 cases and 121 controls, the authors failed to observe those findings. (Moretti, 1989). Expert consensus supports the compatibility of Mesalazine during breastfeeding.

Apriso | Mesalamine 375 Mg Breastfeeding Analsys - 2

Mesalamine while Breastfeeding

CAS Number: 89-57-6

Mesalamine is poorly excreted into breastmilk. However, rather high levels of the mesalamine metabolite N-acetyl-5-ASA appear in breastmilk and its effects on breastfed infants are unknown. A few cases of diarrhea have been reported in infants exposed to mesalamine, although the rate is not high. Most experts consider mesalamine derivatives to be safe during breastfeeding.[1][2][3][4] If mesalamine is required by the mother, it is not a reason to discontinue breastfeeding, but carefully observe breastfed infants for diarrhea during maternal use of mesalamine.

What should I do if already breastfed my kid after using Apriso | Mesalamine 375 Mg?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Apriso | Mesalamine 375 Mg and have used it then do not panic as Apriso | Mesalamine 375 Mg is mostly safe in breastfeeding and should not cause any harm to your baby.

I am nursing mother and my doctor has suggested me to use Apriso | Mesalamine 375 Mg, is it safe?

Definitely, Apriso | Mesalamine 375 Mg is safe in lactation for baby. No wonder your doctor has recommended it.

If I am using Apriso | Mesalamine 375 Mg, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Apriso | Mesalamine 375 Mg

Who can I talk to if I have questions about usage of Apriso | Mesalamine 375 Mg in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week