CAS Number: 1405-86-3
Root of leguminous herb is used. Content: essential oil, flavonoids, tannins, saponins, hydroxi-coumarins.... Unproven effects: anti-ulcerative and expectorant. Indication after Commission E of German Ministry of Health: gastritis, gastric ulcer, cough, bronchitis. Because of mineralocorticoid effects, Pseudoaldosteronism, Hypokalemic palsy, Hypernatremia, Edema, Heart arrhythmias and Arterial Hypertension, a longstanding use or abuse of licorice may be a cause of severe health disorders. May be a cause of abortion and premature labor if taken while pregnancy. Since it has anti-prolactin and estrogenic effects, decrease of milk production can occur within the first weeks after birth. Reportedly, one case of hyperprolactinemia has occurred. There is no proof on its galactagogue effect. Glycyrrhizin is responsible of many effects of Licorice which is excreted in small amount into breast milk. Two infants younger than one months were severely intoxicated (lethargy) after their mothers had drunk an daily average of 2 liters of a beverage containing a mixture of Licorice, Fennel, Anise and Goat's rue. It was assumed to be related to anethol contained in the fennel and anise.
CAS Number: 84775-66-6
Licorice (Glycyrrhiza glabra) root contains glycyrrhizin (also called glycyrrhizic acid or glycyrrhizinic acid) and a mixture of the potassium and calcium salts of glycyrrhizic acid. Glycyrrhizin is metabolized to the active glycyrrhetinic acid in the intestine. Deglycyrrhizinated licorice (DGL) has had glycyrrhizin removed. Licorice is a purported galactogogue, and is included in some Asian proprietary mixtures to increase milk supply; however, no scientifically valid clinical trials support this use. In fact, licorice usually reduces serum prolactin,[1] which might decrease milk production in the early stages of lactation. Women taking licorice have experienced elevated blood presure.[2] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[3] Glycyrrhizin is detectable in the breastmilk of some women taking licorice, but studies measuring glycyrrhetinic acid have not been performed. Licorice has been used safely and effectively in combination with other herbs given to infants as a tea for the short-term treatment of colic.[4] However, two infants whose mothers had an excessive intake of an herbal tea that contained licorice had signs of anethole toxicity.[5] Because both of these papers reported on herbal mixtures, the effect(s) of licorice alone cannot be determined. Licorice and licorice extract are "generally recognized as safe" (GRAS) as foods by the U.S. Food and Drug Administration. Long-term, excessive use of licorice can cause hypertension, hypokalemia, and disturbances of adrenal hormones, and therefore should probably be avoided during nursing. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.
Not much study has been done on safety of Younggaksan | Platycodon Grandiflorus Root 11.7 Mg, Polygala Senega Root 0.5 Mg, Apricot Kernel Oil 0.83 Mg, Glycyrrhizin 8.3 Mg in breastfeeding and its ingredients. Even we do not have complete information about usage of Younggaksan | Platycodon Grandiflorus Root 11.7 Mg, Polygala Senega Root 0.5 Mg, Apricot Kernel Oil 0.83 Mg, Glycyrrhizin 8.3 Mg in breastfeeding so at this point a trained medical professional could be your best bet. If you observe anything abnormal with your baby please contact 911.
If your doctor considers Younggaksan | Platycodon Grandiflorus Root 11.7 Mg, Polygala Senega Root 0.5 Mg, Apricot Kernel Oil 0.83 Mg, Glycyrrhizin 8.3 Mg safe enough to prescribe for you that means its benefits should outweigh its known risks for you.
We are not Sure, Please check with your healthcare provider or doctor.
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