Amantadine 100 Mg while Breastfeeding

For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Amantadine 100 Mg and its risk associated with lactation. We will also discuss the usage of Amantadine 100 Mg and some common side effects associated with Amantadine 100 Mg.

What is Amantadine 100 Mg used for?

Amantadine hydrochloride capsules are indicated for the prophylaxis and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Amantadine hydrochloride capsules are also indicated in the treatment of parkinsonism and drug-induced extrapyramidal reactions. Influenza A Prophylaxis Amantadine hydrochloride capsules are indicated for chemoprophylaxis against signs and symptoms of influenza A virus infection. Because amantadine does not completely prevent the host immune response to influenza A infection, individuals who take this drug may still develop immune responses to natural disease or vaccination and may be protected when later exposed to antigenically related viruses. Following vaccination during an influenza A outbreak, amantadine prophylaxis should be considered for the 2- to 4-week time period required to develop an antibody response. Influenza A Treatment Amantadine hydrochloride capsules are also indicated in the treatment of uncomplicated respiratory tract illness caused by influenza A virus strains especially when administered early in the course of illness. There are no well-controlled clinical studies demonstrating that treatment with amantadine hydrochloride capsules will avoid the development of influenza A virus pneumonitis or other complications in high risk patients. There is no clinical evidence indicating that amantadine hydrochloride capsules are effective in the prophylaxis or treatment of viral respiratory tract illnesses other than those caused by influenza A virus strains. The following points should be considered before initiating treatment or prophylaxis with amantadine hydrochloride capsules. · Amantadine hydrochloride capsules are not a substitute for early vaccination on an annual basis as recommended by the Centers for Disease Control and Prevention Advisory Committee onImmunization Practices. · Influenza viruses change over time. Emergence of resistance mutations could decrease drug effectiveness. Other factors (for example, changes in viral virulence) might also diminish clinical benefit of antiviral drugs. Prescribers should consider available information on influenza drug susceptibility patterns and treatment effects when deciding whether to use amantadine hydrochloride capsules. Parkinson’s Disease/Syndrome Amantadine hydrochloride capsules are indicated in the treatment of idiopathic Parkinson’s disease (Paralysis Agitans), postencephalitic parkinsonism and symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication. It is indicated in those elderly patients believed to develop parkinsonism in association with cerebral arteriosclerosis. In the treatment of Parkinson’s disease, amantadine is less effective than levodopa, (-)-3-(3,4-dihydroxyphenyl)-L-alanine, and its efficacy in comparison with the anticholinergic antiparkinson drugs has not yet been established. Drug-Induced Extrapyramidal Reactions Amantadine hydrochloride is indicated in the treatment of drug-induced extrapyramidal reactions. Although anticholinergic-type side effects have been noted with amantadine when used in patients with drug-induced extrapyramidal reactions, there is a lower incidence of these side effects than that observed with the anticholinergic antiparkinson drugs.

Is Amantadine 100 Mg usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Amantadine 100 Mg low risk for breastfeeding
Amantadine 100 Mg contains only one active ingredient that is Amantadine hydrochloride. We have analyzed the usage of Amantadine hydrochloride in breastfeeding and our analysis suggest that Amantadine hydrochloride poses Low risk for infant while breastfeeding and hence Amantadine 100 Mg itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Amantadine is excreted in human milk. Use is not recommended in nursing mothers.

Amantadine 100 Mg Breastfeeding Analsys

Amantadine hydrochloride while Breastfeeding

Low Risk

CAS Number: 665-66-7

Antiviral used for treatment and prophylaxis of type-A Influenza. Since it is a dopamine agonist is also used to treat Parkinson’s disease. At latest update relevant published data on excretion into breast milk were not found. Because of large volume of distribution and low plasma level observed (Pacifici 1976), a passage of significant amount through breastmilk or side-effects on the infant are not likely to occur. Amantadine reduces plasma levels of prolactin, it has been used to treat galactorrhea caused by the use of dopaminergic neuroleptic drugs (Siever 1981 Correa 1987, Marken 1992, Carvalho 2011), however there is not information about the effect on lactating mothers. Prolactin is important to milk production especially during the first few weeks within birth. Frequent and effective stimulation of the nipple by the infant is essential on the maintenance of breastfeeding. Whether administered during breastfeeding, it would be advisable not to use it in the neonatal period and monitor milk production.

Amantadine 100 Mg Breastfeeding Analsys - 2

Amantadine hydrochloride while Breastfeeding

CAS Number: 768-94-5

It is probably best to avoid amantadine during breastfeeding because of its potential negative effect on lactation.

What should I do if I am breastfeeding mother and I am already exposed to Amantadine 100 Mg?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Amantadine 100 Mg then you shall inform your doctor, But you should not be worried too much as Amantadine 100 Mg comes in category of low risk drug.

I am nursing mother and my doctor has suggested me to use Amantadine 100 Mg, is it safe?

Though Amantadine 100 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.

If I am using Amantadine 100 Mg, will my baby need extra monitoring?

Not much

Who can I talk to if I have questions about usage of Amantadine 100 Mg in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week