Prenate Mini while Breastfeeding

What is Prenate Mini used for?

Is Prenate Mini usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Ascorbic acid while Breastfeeding

CAS Number: 50-81-7

Vitamin C is abundantly present in food. A balanced and comprehensive diet makes vitamin supplementation useless. Any amount of vitamin C taken by the mother as a supplement does not affect significantly the concentration in breast milk of women who are on a varied and balanced diet.

Cholecalciferol while Breastfeeding

CAS Number: 67-97-0

Daily allowance of Vitamin D for the breastfeeding woman is still an issue and a matter of disagreement among experts. Vitamin D is hardly found in common food and mostly synthesized by skin under sunlight stimulus. Low concentration in breast milk is thought to be due to deficient levels in the serum of mothers. As high as 6.400 IU daily doses of Vitamin D given to the mother have been required to normalize the infant serum content of 25-OH Vitamin D. Moderate exposure of mothers to sunlight, avoiding any burning, is probably the most cost-effective measure to fight Vitamin D deficiency in the infant. 1 mg = 40.000 IU.

Pyridoxine hydrochloride while Breastfeeding

CAS Number: 58-56-0

Concentration of vitamin B6 in the breast milk is directly related to the amount present in diet with the possibility of a high increment by an excessive consumption through the diet. Daily allowance of vitamin B6 ranges from 2 to 3 mg. A balanced and varied diet is enough without a need for extra supplementation with this vitamin. Vitamin B6 deficiency is extremely rare since it is widely distributed in many foods. In those cases where supplementation is required, it is recommended not to exceed 40 mg a-day. There are controversial data on the capacity of a high dose of Pyridoxine to inhibit the secretion of Prolactin and suppress the milk production. The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Folic acid while Breastfeeding

CAS Number: 59-30-3

Soluble B group vitamin that is very abundant in green vegetables, legumes and fruits (citric fruits). It is actively excreted in breast milk with priority over maternal folate in such extent that may even cause maternal deficit. Exclusive breastfeeding meets the daily allowances of infant folic acid.The concentration is higher in mature milk (85 micrograms / L) than in colostrum and premature breast milk.Administration to nursing mothers increases slightly the usual concentration of folate in breast milk. Folic acid needs are increased during pregnancy and lactation (500-600 micrograms / day) and in case of taking anticonvulsant medication. No harmful effects have been observed by taking folic acid during lactation. Excess of folic acid is eliminated by the kidneys every day. No supplements are needed if diet and nutritional status are adequate. The American Academy of Pediatrics rates it as a mediation usually compatible with breastfeeding.WHO List of Essential Medicines 2002: compatible with breastfeeding.

Cyanocobalamin while Breastfeeding

CAS Number: 68-19-9

Vitamin B12 exists naturally in milk at a concentration of 1 nanogram / mL (range: 0.3 to 3 ng / mL). Maternal supplementation with cyanocobalamin barely increases milk levels in well-nourished women (Sandberg 1981), but it does improve the levels in women of low socioeconomic status (Sneed 1981). The concentration in colostrum is up to 28 times higher than that of mature milk.The daily requirements for Vitamin B12 are 2.4 micrograms and increase to 2.8 micrograms daily during breastfeeding. Foods rich in vitamin B12 are meat, offal, eggs, dairy products, salmon, sardines, clams and fortified cereals. With a varied and balanced diet no vitamin supplements are needed, but B12 deficiency has been observed in the plasma and milk of women with strict vegetarian diets (vegans), malabsorptive diseases (eg, Crohn's disease, celiac disease), bariatric surgery, poor nutritional status, pernicious anemia, low socio-economic status and in cases of natural disasters or wars. There are numerous publications showing that infants of these mothers are at high risk of disease due to vitamin B12 deficiency, which can lead to anemia, stunting and psychomotor retardation. "Flash pasteurization" applied to breast milk of mothers who are HIV+ does not decrease vitamin B12 concentration. American Academy of Pediatrics: medication usually compatible with breastfeeding (AAP 2001).

Biotin while Breastfeeding

CAS Number: 58-85-5

It is an essential co-enzyme for fat metabolism and other metabolic reactions, which is classified among the vitamin B group. Recommended daily allowance is 10 to 200 μg according to some authorities and 30 to 100 μg to some others. (5 at15 μg for infants, 20 to 30 μg for children, 30 μg for pregnant women and 35 μg for lactating mothers). Biotin is found in the non-fat fraction of breast milk in an amount of 5 to 9 μg/L. Biotin is widely distributed in most foods with a very rare occurrence of deficiency among people who are on adequate diet, nor any case of intoxication is known even with higher doses than recommended for daily intake. At date of latest update, relevant data related to breastfeeding were not found. However, because lack of toxicity a risk due to consumption at recommended dose is unlikely. With an adequate and comprehensive diet, the consumption of vitamin supplementation is not necessary.

Calcium cation while Breastfeeding

Various calcium salts (Acetate, Carbonate, Chloride, Citrate, Phosphate, Gluceptate, Glucobionato, Lactate, Laxctobionato Pidolate, Silicate) are used in the management of hypocalcemia, supplements for treating calcium deficiency states and antacids ( Carbonate and Silicate) Daily requirement of calcium during lactation are 1 g (1.3 g in children under 20 years).Calcium supplements in the diet does not affect the concentration of calcium in milk.Excessive intake of calcium is not good for health. During lactation, consumption of calcium should not exceed 2.5 g a day. WHO List of Essential Medicines 2002 states that it is compatible with breastfeeding.

Ferrous cation while Breastfeeding

CAS Number: 141-01-5

Several ferrous salts of iron (ascorbate, aspartate, citrate, chloride, fumarate, gluconate, lactate, oxalate, succinate, sulfate, glycine sulfate, etc.) are used in oral administration for treating or preventing iron deficiency anemia.Its molecular weight varies from 170 for the fumarate and succinate, and from 280 for lactate and sulfate to 400 for aspartate and ascorbate. Characteristics of iron metabolism in the body make unlikely that it would be excreted in a significant amount into breast milk.It is a medication used for treatment of Neonatal Anemia in premature babies. Iron is excreted in small amounts in human milk, usually being enough for covering the daily needs of infants due to its high bioavailability. There is no correlation between mother's daily intake of iron and its concentration in breast milk.Iron supplementation to the mother does not increase levels of iron in breast milk or infant plasma significantly. Excessive supplementation can reduce the zinc concentration in milk. WHO List of Essential Medicines 2002: compatible with breastfeeding.

Iron while Breastfeeding

Several ferrous salts of iron (ascorbate, aspartate, citrate, chloride, fumarate, gluconate, lactate, oxalate, succinate, sulfate, glycine sulfate, etc.) are used in oral administration for treating or preventing iron deficiency anemia.Its molecular weight varies from 170 for the fumarate and succinate, and from 280 for lactate and sulfate to 400 for aspartate and ascorbate. Characteristics of iron metabolism in the body make unlikely that it would be excreted in a significant amount into breast milk.It is a medication used for treatment of Neonatal Anemia in premature babies. Iron is excreted in small amounts in human milk, usually being enough for covering the daily needs of infants due to its high bioavailability. There is no correlation between mother's daily intake of iron and its concentration in breast milk.Iron supplementation to the mother does not increase levels of iron in breast milk or infant plasma significantly. Excessive supplementation can reduce the zinc concentration in milk. WHO List of Essential Medicines 2002: compatible with breastfeeding.

Iodide ion while Breastfeeding

CAS Number: 7553-56-2

Disinfectant that contains high amount (2-7%) of Iodine in solution with alcohol or water (Lugol's solution) Not absorbed through intact skin of adults. However, it may trespass the inflamed skin, wounds, mucosa surfaces like vagina, in which case can reach concentration in grams in the human serum (1 g = 1,000 milligrams = 1,000,000 micrograms). Normal daily allowance is considered to be as high as 100 to 150 micrograms that increases to 200 – 300 micrograms in pregnancy or nursing period. The latter means less than one third of a milligram. Iodine is concentrated into breast milk with a level that could reach 20 times higher than the concentration in the blood. It has been found higher levels of Iodine, altered results of neonatal screening test for thyroid function, and, transient hypothyroidism in infants whose mothers were exposed to Iodine Povidone. Use should be avoid in the Delivery Room, Operating Room (C-section), Neonatal Units, Toddler admision areas and during the breastfeeding period. Sporadic or inadvertent use, specially on normal skin, does not require special test or procedures because it does not pose higher risk to the child.

Magnesium cation while Breastfeeding

CAS Number: 1309-48-4

Ingested Magnesium does not concentrate into breast milk. Naturally occurring, the mean Magnesium concentration in the milk is 31 mg/L (range 15 – 64 mg/L) and not affected by the ingestion of Magnesium. Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability. Avoid chronic or excessive use. WHO Model List of Essential Medicines 2002: Magnesium oxide is compatible with breastfeeding.

Cyanocobalamin while Breastfeeding

CAS Number: 68-19-9

Vitamin B12 is a normal component of human milk.[1] The recommended daily intake in lactating women is 2.8 mcg and for infants aged 6 months or less is 0.4 mcg.[2] Lactating mothers may need to supplement their diet to achieve the recommended daily intake or to correct a known deficiency. Low doses of vitamin B12 found in B complex or prenatal vitamins increase milk levels only slightly. Higher daily doses of 50 to 100 mcg or more are needed in cases of maternal deficiency. The breastfed infant is not exposed to excessive vitamin B12 in such cases, and their vitamin B12 status should improve if it was previously inadequate. Poor health outcomes in infants with vitamin B12 deficiency include anemia, abnormal skin and hair development, convulsions, failure to thrive, and mental developmental delay. One well-recognized at risk group are exclusively breastfed infants of mothers with B12 deficiency due to minimal or no dietary intake of animal products.[3][4][5][6][7][8][9] Infant vitamin B12 status can be improved through maternal B12 supplementation during pregnancy and lactation.[10][11][12][13] Deficient mothers who miss the opportunity to supplement during pregnancy should still be encouraged to supplement during early lactation since infant vitamin B12 status correlates with milk vitamin B12 levels in breastfed infants up to 6 months of age.[14][15][16][17] Although there are cases reported of exclusively breastfed infants with vitamin B12 deficiency having biochemical and clinical improvement through adequate maternal supplementation alone,[3] direct supplementation of the infant is recommended when such treatments are available.[18][19][8] Flash heat pasteurization of breastmilk does not reduce milk vitamin B12 concentration.[20]

Iodide ion while Breastfeeding

CAS Number: 7553-56-2

Iodine is an essential trace nutrient for all infants that a normal component of breastmilk. Infant requirements are estimated to be 15 mcg/kg daily in fullterm infants and 30 mcg/kg daily in premature infants.[1] Systematic reviews and studies on iodine nutrition found that iodine in breastmilk is adequate in iodine-sufficient countries, but in countries with iodine fortification of foods, many mothers did not obtain adequate iodine and that additional supplementation was desirable.[2][3][4][5] In iodine-deficient areas, supplementation of breastfeeding mothers with iodine appears to be more effective than direct supplementation of the infant in reducing infant iodine deficiency.[6] The American Thyroid Association recommends that breastfeeding women should supplement their diet with a daily oral supplement that contains 150 mcg of iodine, but sustained iodine intake while breastfeeding that exceeds 500 to 1100 mcg daily should be avoided.[7] A survey in the United States between 2011 and 2014 found that only 19% of lactating women used a dietary supplement that contained iodine.[8] The use of excessive amounts of iodine in the mother near term and during breastfeeding (e.g., seaweed soup) can increase breastmilk iodine levels and cause transient hypothyroidism in breastfed infants. The absorption of iodine can be marked after application to open wounds or mucous membranes. Exposure of mothers to unnecessary iodine who are or will be breastfeeding should be avoided or minimized to the extent possible by avoiding its use on maternal mucous membranes (e.g., vaginal use, wound therapy), avoiding prolonged contact time, avoiding repeated applications, and applying it to the smallest possible surface areas of the body. It is possible that maternal exposure to iodine near term could interfere with thyroid studies done as a part of newborn screening tests.

Magnesium cation while Breastfeeding

CAS Number: 1309-48-4

No information is available on the clinical use of magnesium oxide during breastfeeding. However, other magnesium salts have been studied. A study on the use of magnesium hydroxide during breastfeeding found no adverse reactions in breastfed infants. Intravenous magnesium increases milk magnesium concentrations only slightly. Oral absorption of magnesium by the infant is poor, so maternal magnesium hydroxide is not expected to affect the breastfed infant's serum magnesium. Magnesium oxide supplementation during pregnancy might delay the onset of lactation, but it can be taken during breastfeeding and no special precautions are required.

What should I do if already breastfed my kid after using Prenate Mini?

I am nursing mother and my doctor has suggested me to use Prenate Mini, is it safe?

If I am using Prenate Mini, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Prenate Mini in breastfeeding?