I am a breastfeeding mother and i want to know if it is safe to use 177Lu-dotatate? Is 177Lu-dotatate safe for nursing mother and child? Does 177Lu-dotatate extracts into breast milk? Does 177Lu-dotatate has any long term or short term side effects on infants? Can 177Lu-dotatate influence milk supply or can 177Lu-dotatate decrease milk supply in lactating mothers?
177Lu-dotatate is a radiolabeled somatostatin analog indicated for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors. No information is available on the use of 177Lu-dotatate during breastfeeding. The manufacturer recommends that breastfeeding be discontinued during 177Lu-dotatate therapy and for 2.5 months following the last dose, which would usually mean permanently discontinuing breastfeeding of the current infant. Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[1]
Disclaimer:
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.