Question

I am a breastfeeding mother and i want to know if it is safe to use EC 258-416-5? Is EC 258-416-5 safe for nursing mother and child? Does EC 258-416-5 extracts into breast milk? Does EC 258-416-5 has any long term or short term side effects on infants? Can EC 258-416-5 influence milk supply or can EC 258-416-5 decrease milk supply in lactating mothers?

EC 258-416-5 lactation summary

EC 258-416-5 is safe in breastfeeding
  • DrLact safety Score for EC 258-416-5 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of EC 258-416-5 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that EC 258-416-5 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of EC 258-416-5 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EC 258-416-5 usage in lactation

Opioid drug derived from pethidine. Contraindicated for those children younger than 2 year old. Indiscriminate use for treatment of gastroenteritis is not justified. Most acute diarrheic disorders are self-limijted conditions. WHO’s Oral Rehydration Solutions and appropriate nutritional support are recommended. Excreted into breast milk in non-significant levels. Its low oral bioavailability makes it difficult to acceed the infant serum. The American Academy of Pediatrics rates it as compatible with breastfeeding.

Answer by DrLact: About EC 258-416-5 usage in lactation

Use of EC 258-416-5 during breastfeeding is unlikely to affect the infant.
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