Question

I am a breastfeeding mother and i want to know if it is safe to use Thiethylpipezazine? Is Thiethylpipezazine safe for nursing mother and child? Does Thiethylpipezazine extracts into breast milk? Does Thiethylpipezazine has any long term or short term side effects on infants? Can Thiethylpipezazine influence milk supply or can Thiethylpipezazine decrease milk supply in lactating mothers?

Thiethylpipezazine lactation summary

Thiethylpipezazine is unsafe in breastfeeding
  • DrLact safety Score for Thiethylpipezazine is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Thiethylpipezazine may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Thiethylpipezazine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Thiethylpipezazine .
  • It is recommended to evaluate the advantage of not breastfeeding while using Thiethylpipezazine Vs not using Thiethylpipezazine And continue breastfeeding.
  • While using Thiethylpipezazine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Thiethylpipezazine usage in lactation

It is a first generation antihistaminic and phenothiazine drug with a sedative effect. Isolated dose is considered to be compatible with BF. Used in Ménière’s disease, we suggest to choose a alternative safer drug.

Answer by DrLact: About Thiethylpipezazine usage in lactation

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of Thiethylpipezazine for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Thiethylpipezazine Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[6]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.